Ingredients: Bacopa, Tulsi (Holy Basil), Sceletium, Cordyceps, Lion’s Mane, Gotu Kola (Centella), Ashwagandha, Reishi, Ginkgo, Lemon Balm & Black Pepper
Who It’s For
Adults seeking a calm, focus-enhancing, mood-stabilising cognitive formula to sharpen attention and memory, improve mental clarity, and support resilience under stress.
It is beneficial for individuals with attention difficulties, as well as those seeking to achieve flow states and improve everyday performance, alongside a balanced approach that includes sleep, exercise, nutrient-rich meals, and professional guidance where necessary.
Health Benefits Summary
Phyto Nootropics promotes clear focus, quicker thinking, and better memory, while supporting emotional balance, a calm yet alert state, and steady daytime energy without overstimulation. It helps reduce anxious overdrive, smooth stress responses, and strengthen immune readiness that underpins neuroimmune balance. By enhancing cellular antioxidant defences and neuroplasticity, it also boosts long-term brain resilience and overall vitality.
Detailed Health Benefits
• Calm Focus & Attention
How it Helps: Settles mental noise and supports sustained attention and task follow-through.
How it Works: Nutrients and nootropics foster a calm-alert state, enhance signal-to-noise in cortical networks, and support neurovascular delivery for steadier concentration.
• Memory, Learning & Processing Speed
How it Helps: Aids working memory, recall, and smoother cognitive throughput during demanding tasks.
How it Works: Neurotrophic and synaptic-supportive compounds enhance plasticity (e.g., BDNF/NGF pathways) and neurotransmitter efficiency.
• Mood & Stress Resilience
How it Helps: Reduces anxious tension and stress-fatigue while supporting a positive, motivated outlook.
How it Works: Adaptogenic actives modulate HPA-axis tone and balance GABA/serotonin dynamics for steadier affect and coping.
• Daytime Energy & Cognitive Stamina
How it Helps: Promotes clean, sustainable mental energy without jitters or crash.
How it Works: Mitochondrial and antioxidant support improve neuronal energy handling and reduce oxidative drag on cognition.
• Immune Readiness & Neuroimmune Balance
How it Helps: Supports a balanced immune tone that underpins cognitive clarity and day-to-day resilience.
How it Works: Select botanicals and fungi provide β-glucans and polyphenols that help normalise cytokine signalling and support barrier and microglial balance.
Key Ingredients – Evidence-Based Actions
• Bacopa (Bacopa monnieri)
How it Helps: Improves attention, processing speed, and aspects of memory with sustained use.
Why it Works: Bacosides modulate cholinergic/serotonergic signalling, antioxidant defences, and synaptic plasticity.
Research:
– Meta-analysis of RCTs on cognitive effects: https://www.sciencedirect.com/science/article/abs/pii/S0378874113008027
– Evidence overview (clinical summaries): https://www.ncbi.nlm.nih.gov/books/NBK589635/
• Tulsi / Holy Basil (Ocimum tenuiflorum)
How it Helps: Calms stress-linked anxiety and supports mood and sleep quality for better daytime performance.
Why it Works: Phenolics/terpenes temper HPA-axis hyperarousal and modulate GABAergic/inflammatory pathways.
Research:
– DB-crossover RCT (immunomodulatory/anxiolytic signals): https://pubmed.ncbi.nlm.nih.gov/21619917/
– Human overview & safety: https://pmc.ncbi.nlm.nih.gov/articles/PMC5376420/
• Sceletium (Sceletium tortuosum)
How it Helps: Smooths anxious hyperarousal and supports calm focus and mood.
Why it Works: Dual PDE4 inhibition + serotonin reuptake modulation with fMRI evidence of amygdala-calming effects.
Research:
– Pharmaco-fMRI RCT (reduced amygdala reactivity): https://pubmed.ncbi.nlm.nih.gov/23903032/ / https://www.nature.com/articles/npp2013183
• Cordyceps (Cordyceps militaris / sinensis)
How it Helps: Cognitive: emerging evidence for memory/learning support and neuroprotection; Immune: helps maintain balanced innate responses and vitality.
Why it Works: Cordycepin and polysaccharides influence neuroinflammatory and antioxidant pathways; preclinical models show learning/memory benefits, while human data for immunity and wellness are stronger.
Research (cognition & neuroprotection):
– Preclinical: Cordyceps polypeptide improved learning/memory (scopolamine model). https://pmc.ncbi.nlm.nih.gov/articles/PMC5874985/ (PMC)
– Review on Cordyceps & neurodegeneration (AD context; mechanisms). https://www.mdpi.com/1422-0067/26/11/5403 (MDPI)
Research (immune/clinical context):
– Cordyceps polysaccharides—immunomodulatory review. https://www.mdpi.com/1420-3049/29/21/5107 (MDPI)
– 2024 human RCT (fermented C. militaris beverage; wellness/immune endpoints). https://pubmed.ncbi.nlm.nih.gov/38580687/
• Lion’s Mane (Hericium erinaceus)
How it Helps: Supports cognitive performance and mood under stress; emerging nootropic benefits.
Why it Works: Hericenones/erinacines promote NGF-related neurotrophic activity and antioxidant support.
Research:
– DB-RCT in MCI (cognitive improvement at 16 weeks): https://pubmed.ncbi.nlm.nih.gov/18844328/
– Narrative/clinical overview (recent human data): https://pmc.ncbi.nlm.nih.gov/articles/PMC10675414/
• Gotu Kola (Centella asiatica)
How it Helps: Aids working memory and calm alertness; supportive in vascular cognitive contexts.
Why it Works: Triterpenes support microcirculation, antioxidant tone, and synaptic plasticity.
Research:
– Human alertness/cognition signals: https://www.nature.com/articles/s41598-017-09823-9
– Clinical summaries (vascular cognitive impairment; refs within): https://www.alzdiscovery.org/cognitive-vitality/ratings/centella-asiatica
• Ashwagandha (Withania somnifera)
How it Helps: Enhances stress resilience, sleep quality, and cognitive performance.
Why it Works: Withanolides modulate the HPA axis and GABA/serotonin pathways; multiple RCTs/meta-analyses show reduced stress and anxiety, as well as improved cognition.
Research:
– Systematic review/meta-analysis (stress/anxiety/sleep): https://pmc.ncbi.nlm.nih.gov/articles/PMC8762185/
– 2025 meta-analysis update (RCT synthesis): https://pmc.ncbi.nlm.nih.gov/articles/PMC11800443/
• Reishi (Ganoderma lucidum)
How it Helps: Cognitive: emerging neuroprotective signals (learning/memory domains) with limited human data; Immune: helps balance innate/adaptive responses for systemic resilience.
Why it Works: Polysaccharides and triterpenes modulate microglial activation, oxidative stress, and neurovascular factors; β-glucans support immune tone.
Research (cognition & neuroprotection):
– Nature portfolio study: reishi extract improved memory under hypobaric stress (animal model). https://www.nature.com/articles/s41598-020-65812-5 (Nature)
– 2024 review on G. lucidum bioactivity, incl. cognitive/AD models. https://www.mdpi.com/1420-3049/29/11/2516 (MDPI)
Research (immune/clinical context):
– 2023 RCT: β-glucan from reishi modulated immune markers in healthy adults. https://pubmed.ncbi.nlm.nih.gov/36766186/
• Ginkgo (Ginkgo biloba)
How it Helps: Supports attention, processing, and daily functioning, signalling mild cognitive impairment/age-related changes.
Why it Works: Terpene lactones/flavonol glycosides improve microcirculation and mitochondrial/antioxidant defences.
Research:
– Clinical review of EGb 761 in cognitive disorders: https://pmc.ncbi.nlm.nih.gov/articles/PMC10041984/
• Lemon Balm (Melissa officinalis)
How it Helps: Calms anxiety and can aid acute cognitive performance and sleep quality.
Why it Works: Rosmarinic acid-rich extracts modulate the GABA and cholinergic systems.
Research:
– Acute cognition/mood in healthy adults: https://pubmed.ncbi.nlm.nih.gov/12062586/; https://pubmed.ncbi.nlm.nih.gov/12888775/
– Recent RCT on sleep quality: https://pmc.ncbi.nlm.nih.gov/articles/PMC11644815/
• Black Pepper (Piperine co-extract)
How it Helps: Enhances absorption of select actives for a stronger, faster onset of benefits.
Why it Works: Piperine inhibits intestinal/hepatic glucuronidation, markedly increasing bioavailability.
Research:
– Human PK study (~2000% ↑ curcumin bioavailability with 20 mg piperine): https://pubmed.ncbi.nlm.nih.gov/9619120/
Dosage Guidelines
• Prevention (daily calm-focus): 1 capsule with breakfast.
• Maintenance (ongoing support): 1 capsule twice daily (morning and mid-afternoon).
• Therapeutic (active support phase): 2 capsules twice daily for 6–8 weeks, then reduce to Maintenance; avoid dosing within 6 hours of bedtime if you feel overstimulated.
Tips: Pair the morning dose with a protein-rich breakfast; keep caffeine consumption moderate; schedule deep work blocks 60–180 minutes after the dose.
Warnings & Interactions
• Not for pregnancy or breastfeeding unless advised by a clinician.
• Sceletium: Serotonergic/PDE4 activity—avoid with SSRIs/SNRIs/MAOIs or other serotonergic agents; do not combine with potent PDE4 inhibitors.
• Ginkgo: May increase bleeding risk—caution with anticoagulants/antiplatelets; avoid with seizure disorders.
• Rhodiola: Can be activating; avoid near bedtime and use caution in bipolar spectrum.
• Bacopa: May cause mild GI upset or drowsiness—take with food; start low if sensitive.
• Black pepper (piperine): May alter drug absorption; separate from narrow-therapeutic-index medicines.
• General: Stop use if adverse reactions occur. Keep out of reach of children.
⚠️ Disclaimer
Natural herbal supplement for general well-being.
Not intended to diagnose, treat, cure, or prevent any disease.
Statements reflect traditional use and general wellness support and have not been evaluated by SAHPRA.
Consult a healthcare professional before use—especially if you have a medical condition or take prescription medicines (e.g., anticoagulants, antidepressants, thyroid/antibiotics, narrow-therapeutic-index drugs), or are managing mood/attention disorders.
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