Ingredients: Echinacea, Olive Leaf Extract, Cancer Bush (Sutherlandia frutescens), Elderberries, Ashwagandha, Moringa, Black Seed, Vitamin C, MSM, Coenzyme Q10, L-Carnitine
Who It’s For
IMMUNE BOOSTING FORMULA WITH VITAMIN C & COENZYME Q10
Adults seeking daily support for immune health, upper-respiratory function, antioxidant protection, balanced inflammation, and recovery—especially during periods of increased exposure, stress, fatigue, or seasonal changes. Best used alongside a nutrient-rich diet, regular movement, stress management, good sleep, and, where appropriate, guidance from a healthcare professional.
Health Benefits Summary
Phyto Defence is designed to strengthen the body’s natural defences by supporting both innate and adaptive immune responses. It encourages quicker and more effective reactions to everyday immune challenges, helps reduce the duration and severity of seasonal symptoms, and maintains healthy mucosal and respiratory barriers. Additionally, it boosts antioxidant protection to shield immune cells and tissues from oxidative stress, supports balanced inflammation to prevent overreaction or exhaustion, and supplies cellular energy to support immune function and recovery. These combined actions help maintain a strong, stable, and well-regulated immune system for long-term vitality.
Health Benefits Detailed
• Everyday immune readiness
How it Helps: Promotes efficient recognition and response to common immune challenges such as seasonal shifts or crowded environments.
Why it Works: Immunomodulatory plant compounds help “prime” immune cells (such as neutrophils, NK cells, and lymphocytes) so they are ready to respond without overreacting, supporting more balanced cytokine and antibody responses.
• Upper-respiratory comfort & recovery
How it Helps: May reduce the duration and intensity of acute upper-respiratory symptoms and support quicker recovery.
Why it Works: Evidence from clinical trials on selected ingredients shows improvements in upper-respiratory symptom scores and duration, while mucosal-supportive nutrients help protect and soothe delicate respiratory linings.
• Antioxidant support for immune resilience
How it Helps: Protects immune cells and barrier tissues from oxidative damage that can weaken defences.
Why it Works: Antioxidant nutrients and plant polyphenols neutralise reactive oxygen species, regenerate endogenous antioxidant systems, and support redox-sensitive immune signalling pathways.
• Inflammation balance & long-term immune health
How it Helps: Helps calm excessive, draining inflammation while maintaining a robust protective response.
Why it Works: Key compounds modulate pro- and anti-inflammatory cytokines (for example, IL-6, TNF-α, IL-10) and signalling pathways, helping to prevent chronic low-grade inflammation that can undermine immune efficiency over time.
• Energy & recovery support for immune function
How it Helps: Supports physical resilience, post-illness recovery, and the energy demands of an active immune system.
Why it Works: Mitochondrial cofactors and metabolic nutrients help improve cellular ATP production and efficient fuel use, which immune cells rely on during activation and repair processes.
Key Ingredients – Evidence-Based Actions
• Echinacea (Echinacea purpurea)
How it Helps: Supports upper respiratory immune defence and may reduce the risk and duration of certain respiratory infections.
Why it Works: Alkamides and polysaccharides interact with innate immune receptors, influencing cytokine production and helping to reduce the frequency of infection episodes and antibiotic use in some clinical trials. (ScienceDirect)
https://eurjmedres.biomedcentral.com/articles/10.1186/s40001-021-00499-6
— RCT in children: Echinacea reduced respiratory tract infections and antibiotic use
https://www.clinicalnutritionespen.com/article/S2405-4577(25)00285-2/abstract
— 2025 meta-analysis: E. purpurea reduced URTI episode incidence and treatment duration
• Olive Leaf Extract (oleuropein / hydroxytyrosol-rich)
How it Helps: Provides antimicrobial and anti-inflammatory support relevant to respiratory and systemic immune stress.
Why it Works: Olive leaf polyphenols inhibit pathogen replication, reduce inflammatory markers, and mitigate oxidative stress; recent trials in viral respiratory illnesses report improved clinical parameters. (PubMed)
https://pubmed.ncbi.nlm.nih.gov/36319585/
— RCT in COVID-19 patients: olive leaf extract improved vital signs and oxygen saturation
https://www.mdpi.com/2076-3921/12/8/1509
— 2023 review: olive leaf extract shows anti-inflammatory and antioxidant properties
• Cancer Bush (Sutherlandia frutescens)
How it Helps: Traditional southern-African immune and convalescence support; helps modulate immune responses and inflammation.
Why it Works: Experimental work demonstrates that Sutherlandia extracts influence macrophage function and cytokine/chemokine production, indicating potential immunomodulatory and anti-inflammatory effects. (PLOS)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160994
— Study: S. frutescens demonstrated immune-stimulatory and modulatory activity in macrophages
https://pmc.ncbi.nlm.nih.gov/articles/PMC5004858/
— Ex vivo work: S. frutescens altered cytokine/chemokine production in murine immune cells
• Elderberries (Sambucus nigra)
How it Helps: Supports shorter and less severe upper-respiratory symptom episodes when taken at onset.
Why it Works: Anthocyanin-rich extracts show antiviral activity and may modulate inflammatory cytokines; meta-analyses of RCTs report reduced duration and severity of viral URTI symptoms. (PubMed)
https://pubmed.ncbi.nlm.nih.gov/30670267/
— 2019 meta-analysis: elderberry supplementation reduced duration and severity of URTI symptoms
https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-021-03283-5
— 2021 review: elderberry is considered a generally safe adjunct for viral respiratory illness
• Ashwagandha (Withania somnifera)
How it Helps: Adaptogenic support for stress-related immune fatigue; improves selected immune markers in healthy adults.
Why it Works: Withanolide-rich extracts modulate innate and adaptive immune parameters (immunoglobulins, cytokines, T- and NK-cell subsets) in RCTs, while also lowering stress, which indirectly supports immune resilience. (PMC)
https://pmc.ncbi.nlm.nih.gov/articles/PMC8397213/
— Randomised, double-blind trial: ashwagandha extract improved multiple immune markers in healthy subjects
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.761655/full
— Protocol/overview: Ashwagandha explored as an immune-supportive adjunct with vaccination
• Moringa (Moringa oleifera)
How it Helps: Nutrient-dense immune support; emerging human data suggest improved immune indices in vulnerable groups.
Why it Works: Leaves provide vitamins, minerals, and polyphenols with antioxidant and immunomodulatory effects; supplementation has been associated with increased CD4+ counts and improved inflammatory markers in some cohorts. (PMC)
https://pmc.ncbi.nlm.nih.gov/articles/PMC12452103/
— 2025 meta-analysis: Moringa supplementation significantly increased CD4+ T-cell counts in PLHIV
https://pmc.ncbi.nlm.nih.gov/articles/PMC8722362/
— RCT: Moringa leaf supplementation associated with improved CD4 count in HIV patients on ART
• Black Seed (Nigella sativa, thymoquinone-rich)
How it Helps: Broad immune and respiratory support with human data in viral illness and URTI complaints.
Why it Works: Thymoquinone and other constituents show antiviral, antioxidant, and anti-inflammatory actions; clinical studies suggest improved viral clearance, symptom scores, and immunological markers. (ScienceDirect)
https://www.sciencedirect.com/science/article/pii/S0965229921001102
— Open-label RCT: black seed oil improved symptom resolution and viral clearance in COVID-19
https://www.mdpi.com/2076-3921/12/7/1340
— 2023 review: Nigella sativa shows immunomodulatory potential across multiple models
• Vitamin C (ascorbic acid)
How it Helps: Core immune nutrient supporting barrier integrity, leukocyte function, and antioxidant defence.
Why it Works: Vitamin C concentrates in immune cells, enhances chemotaxis, phagocytosis, and microbial killing, and supports epithelial barriers; deficiency is associated with increased susceptibility to infection and slower recovery. (MDPI)
https://www.mdpi.com/2072-6643/9/11/1211
— Key review: vitamin C supports multiple innate and adaptive immune functions
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.574029/full
— Review: vitamin C in the prevention and treatment of respiratory infections
• MSM (Methylsulfonylmethane)
How it Helps: Supports the balance of inflammation and immune resilience, particularly in response to physical or oxidative stress.
Why it Works: Human studies have shown that MSM can blunt the rise in pro-inflammatory cytokines after exercise and shift gene expression toward better immune and antioxidant responses. (PMC)
https://pmc.ncbi.nlm.nih.gov/articles/PMC5097813/
— Study: MSM supplementation modulated cytokine response to exercise in humans
https://pubmed.ncbi.nlm.nih.gov/PMC12225506/
— 2023 work: MSM improved markers of inflammation management and innate immune response post-exercise
• Coenzyme Q10 (CoQ10)
How it Helps: Antioxidant and mitochondrial support that underpins immune cell energy and inflammation control.
Why it Works: CoQ10 participates in electron transport and acts as a lipid-phase antioxidant; meta-analyses have shown improvements in oxidative stress biomarkers and reductions in inflammatory markers in various conditions. (PMC)
https://pmc.ncbi.nlm.nih.gov/articles/PMC10442645/
— 2023 meta-analysis: CoQ10 reduced markers of inflammation and improved antioxidant status
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2023.1191290/full
— Systematic review/meta-analysis: CoQ10 alleviated inflammatory and oxidative-stress markers
• L-Carnitine
How it Helps: Supports energy metabolism in tissues and may help maintain immune-related inflammatory balance and promote recovery.
Why it Works: L-carnitine facilitates the transport of fatty acids into mitochondria; trials suggest effects on inflammatory indices (e.g., the neutrophil-to-lymphocyte ratio) and NK-cell activity, indicating improved immune and metabolic efficiency. (PubMed)
https://pubmed.ncbi.nlm.nih.gov/25951165/
— RCT: pre-operative L-carnitine reduced the neutrophil-to-lymphocyte ratio in CABG patients
https://rrtjournal.biomedcentral.com/articles/10.1186/s41100-015-0004-0
— Study: L-carnitine increased NK-cell activity and improved cardiac parameters in dialysis patients
Dosage Guidelines
• Prevention (daily immune resilience): 1 capsule with breakfast.
• Maintenance (ongoing support): 1 capsule twice daily (morning and late afternoon).
• Therapeutic (active support phase): 2 capsules twice daily for 8–12 weeks, then reduce to Maintenance for continued support.
Tips: Combine with 7–9 hours of sleep, regular moderate exercise, a colourful, whole-foods diet, stress-management practices (such as breathing, prayer/meditation, or spending time in nature), adequate hydration, and, where appropriate, clinician-guided vitamin D and zinc supplementation.
Warnings & Interactions
- Not a substitute for medical care in high or persistent fever, shortness of breath, chest pain, recurrent infections, unexplained weight loss, or if you are immunocompromised—seek professional evaluation.
- Pregnancy & Breastfeeding: Safety data for ashwagandha, black seed, high-dose Moringa extracts, and high-dose CoQ10/L-carnitine are limited—use only under professional supervision.
- Auto-immune conditions: Echinacea, Cancer Bush, Moringa, Ashwagandha, and Black Seed are immunomodulatory; use cautiously and under clinician guidance in auto-immune disease or transplant/immunosuppressant therapy.
- Blood pressure & blood sugar: Black Seed and Moringa may modestly lower BP or glucose—monitor if on antihypertensives or antidiabetics.
- Anticoagulants/antiplatelets: Black Seed and high-dose antioxidant regimens may influence clotting or platelet function—use caution with warfarin and similar medicines.
- CoQ10: May reduce warfarin effect; monitor INR with your clinician.
- Allergies: Avoid if known hypersensitivity to any listed ingredient (including Asteraceae family for Echinacea).
- Discontinue if adverse reactions occur. Keep out of reach of children.
⚠️ Disclaimer
Natural herbal supplement for general well-being.
Not intended to diagnose, treat, cure, or prevent any disease.
Statements reflect traditional use and general wellness support and have not been evaluated by SAHPRA.
Consult a healthcare professional before use—especially if pregnant, breastfeeding, immunocompromised, on chronic medication (including anticoagulant/antiplatelet, antidiabetic, antihypertensive, thyroid or immunosuppressive therapies), or if you have persistent or severe symptoms.
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