Ingredients: Feverfew, Lavender, Rosemary, Ginkgo, White Willow Bark, Passionflower, Magnesium Citrate
Who It’s For
Adults seeking a calming, multi-pathway approach to head pain—for tension headaches, stress-related head discomfort, migraines (including aura), and “tight neck/shoulder” headaches—should consider hydration, regular meals, sleep hygiene, screen and posture breaks, and seek clinician guidance where necessary.
Health Benefits Summary
Headpro aims to reduce headache severity and frequency, soothe the nervous system, and ease muscular tension, all while promoting healthy blood flow to the brain. It supports steady vascular tone, decreases stress-related reactivity, and relieves discomfort in neck and temporal muscles, helping to alleviate pain and pressure, improve daily comfort, and maintain clear focus without intense stimulation.
Detailed Health Benefits
• Tension Release & Muscular Ease
How it Helps: Relaxes tight neck/shoulder/scalp muscles that often trigger or perpetuate headaches.
How it Works: Calming, antispasmodic and analgesic actions help down-regulate nociceptive signalling and relieve myofascial tension.
• Migraine Frequency & Intensity Support
How it Helps: Aids in reducing the number of monthly migraine days and the severity of attacks.
How it Works: Vascular-neurocalming nutrients and botanicals modulate trigeminovascular reactivity, stabilise neuronal excitability, and support healthy platelet/endothelial function.
• Calm Focus & Stress Resilience
How it Helps: Eases anxious tension and promotes a clearer, steadier mood during head-pain cycles.
How it Works: Gentle nervines support GABAergic calm, while adaptogenic/anti-inflammatory effects reduce stress-linked headache triggers.
• Circulation & Oxygen Delivery
How it Helps: Encourages healthy microcirculation and comfort in the temples/occiput during effort or screen work.
How it Works: Vasoactive phytonutrients support endothelial tone and promote comfortable cerebral blood flow dynamics.
• Recovery After an Episode
How it Helps: Shortens lingering heaviness and helps restore normal function after a headache day.
How it Works: Antioxidant and membrane-stabilising actions help resolve residual inflammatory signalling and oxidative stress.
Key Ingredients – Evidence-Based Actions
• Feverfew (Tanacetum parthenium)
How it Helps: A traditional migraine-prophylaxis herb; standardised extracts show reductions in attack frequency in some trials (overall evidence is mixed).
Why it Works: Parthenolide and related sesquiterpene lactones modulate platelet aggregation, serotonin release, and inflammatory mediators in trigeminovascular pathways.
Research:
– RCT (MIG-99 CO₂ extract 6.25 mg t.i.d.): reduced migraine frequency vs placebo. https://pubmed.ncbi.nlm.nih.gov/16232154/ (PubMed)
– Dose-finding RCT (MIG-99). https://pubmed.ncbi.nlm.nih.gov/12230594/ (PubMed)
– Cochrane-style review: overall evidence is inconsistent/limited. https://pmc.ncbi.nlm.nih.gov/articles/PMC7133498/ (PMC)
• Lavender (Lavandula spp., aromatics)
How it Helps: Provides acute relief for migraine discomfort and promotes relaxation; preventive evidence is limited/mixed.
Why it Works: Volatile terpenes (e.g., linalool) may reduce central pain perception and sympathetic arousal, supporting anxiolysis and improved sleep quality in specific settings.
Research:
– Placebo-controlled trial (inhaled lavender during attacks): reduced migraine severity. https://pubmed.ncbi.nlm.nih.gov/22517298/ (PubMed)
– Review including the 2012 RCT and later prophylaxis data (mixed). https://pmc.ncbi.nlm.nih.gov/articles/PMC3612440/; https://pmc.ncbi.nlm.nih.gov/articles/PMC10822728/ (PMC)
• Rosemary (Rosmarinus officinalis / Salvia rosmarinus)
How it Helps: Complementary analgesic/anti-inflammatory and antispasmodic support for tension-type headache comfort.
Why it Works: Carnosic acid and rosmarinic acid modulate COX-2/NF-κB pathways and nociceptive signalling; human headache-specific trials are limited (supportive preclinical and general analgesic data).
Research:
– Comprehensive review of anti-inflammatory/analgesic actions. https://pmc.ncbi.nlm.nih.gov/articles/PMC7491497/; https://www.mdpi.com/1420-3049/27/3/609 (PMC)
• Ginkgo (Ginkgo biloba)
How it Helps: Supports cerebral microcirculation and may help migraine with aura parameters (emerging evidence).
Why it Works: Flavonol glycosides and terpenes (incl. ginkgolide B) influence endothelial function and platelet-activating factor pathways.
Research:
– Prophylaxis in migraine with aura (ginkgolide B): decreased frequency/duration. https://pubmed.ncbi.nlm.nih.gov/19415441/ (PubMed)
– Combination complex in paediatric migraine (includes ginkgolide B + Mg + CoQ10 + riboflavin): frequency reduction. https://pubmed.ncbi.nlm.nih.gov/20872034/ (PubMed)
• White Willow Bark (Salix spp., salicin source)
How it Helps: Analgesic support for head/neck discomfort and post-episode aches; non-acetylated salicylates are aspirin-like—see Warnings.
Why it Works: Salicin is metabolised to salicylic derivatives that inhibit cyclo-oxygenase and prostaglandin synthesis.
Research:
– Review of efficacy/safety in pain conditions. https://pubmed.ncbi.nlm.nih.gov/25997859/; https://www.amjmed.com/article/S0002-9343(00)00442-3/fulltext (PubMed)
– USP safety review (dosage/safety overview). https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-1007-5206.pdf (Thieme)
• Passionflower (Passiflora incarnata)
How it Helps: Calms anxious tension and promotes relaxation/sleep—useful when stress precipitates headaches.
Why it Works: Flavonoids and harmala alkaloids may enhance GABAergic signalling and reduce autonomic arousal.
Research:
– Double-blind RCT vs oxazepam in generalised anxiety (comparable efficacy with fewer performance side-effects). https://pubmed.ncbi.nlm.nih.gov/11679026/; https://pmc.ncbi.nlm.nih.gov/articles/PMC7766837/ (PubMed)
• Magnesium Citrate
How it Helps: Possibly effective for migraine prophylaxis; supports neuromuscular relaxation and calm vascular tone.
Why it Works: Cofactor for ATP-dependent ion pumps and NMDA modulation; deficiency increases neuronal excitability and cortical spreading depression susceptibility.
Research:
– RCT: 600 mg/day magnesium dicitrate reduced migraine attack frequency. https://pubmed.ncbi.nlm.nih.gov/8792038/ (PubMed)
– Systematic review: Grade C (possibly effective) for prevention; citrate highlighted. https://pubmed.ncbi.nlm.nih.gov/29131326/; overview chapter. https://www.ncbi.nlm.nih.gov/books/NBK507271/ (PubMed)
Dosage Guidelines
• Prevention (daily head-comfort): 1 capsule with breakfast.
• Maintenance (ongoing support): 1 capsule twice daily (morning & late afternoon).
• Therapeutic (active phase): 2 capsules at onset, then one capsule every 8–12 hours as needed (max 3/day for up to 3 days/week). For frequent migraines, use daily as Maintenance and work with your clinician.
Tips: Hydrate, limit alcohol and skipped meals, manage light/screen glare, and practise neck/shoulder mobility. Keep a headache diary to identify triggers.
Warnings & Interactions
• Pregnancy & breastfeeding: Not recommended (feverfew, willow, ginkgo, passionflower lack sufficient safety data; willow salicylates are contraindicated in late pregnancy).
• Bleeding risk: Ginkgo and white willow may increase bleeding tendency. Avoid with warfarin, DOACs, high-dose NSAIDs/aspirin, bleeding disorders, or before surgery.
• Salicylate sensitivity/Reye’s: Avoid white willow if salicylate-allergic, on aspirin-sensitive asthma protocols, or in children/teens with viral illness (Reye’s risk).
• Feverfew: Avoid in pregnancy; may cause mouth irritation if chewed (use encapsulated). Possible interactions with anticoagulants/antiplatelets.
• Lavender & passionflower: May increase sedation—use caution with CNS depressants; avoid oral essential-oil ingestion.
• Magnesium citrate: May cause loose stools; separate by 2 hours from thyroid meds, certain antibiotics, or bisphosphonates.
• Allergy: Avoid if allergic to any listed plants.
• Discontinue if adverse reactions occur. Keep out of reach of children.
⚠️ Disclaimer
Natural herbal supplement for general well-being.
Not intended to diagnose, treat, cure, or prevent any disease.
Statements reflect traditional use and general wellness support and have not been evaluated by SAHPRA.
Consult a healthcare professional before use—especially if pregnant, breastfeeding, on anticoagulant/antiplatelet therapy, using CNS depressants, salicylate-sensitive, or managing chronic neurological/bleeding conditions.