Ingredients: Ashwagandha, Maca, Sage, Dong Quai, Tribulus, Chasteberry (Vitex), Rhodiola, Passionflower
Who It’s For
Women seeking a gentle, non-estrogenic approach to endocrine balance and hot-flash relief, especially those who are oestrogen-sensitive or prefer to avoid phyto-oestrogens. Designed to support emotional stability, energy, sleep quality, thermoregulation, and menopausal comfort alongside whole-food nutrition, stress management, movement, and clinical guidance where needed.
Health Benefits Summary
EstroClear promotes hormonal harmony without introducing oestrogen-like compounds, making it suitable for women who are oestrogen-sensitive or wish to avoid phyto-oestrogens. It supports smooth endocrine communication, balanced stress responses, and a stable mood, while helping to reduce hot flashes, night sweats, and energy fluctuations. By calming the nervous system, enhancing resilience, and improving sleep quality, it restores comfort during hormonal transitions such as perimenopause or menopause. The non-estrogenic design helps the body’s own regulatory systems maintain emotional balance, thermoregulatory control, cognitive clarity, and long-term vitality, naturally, safely, and without hormonal stimulation.
Detailed Health Benefits
• Vasomotor Balance (Hot Flashes & Night Sweats)
How it Helps: Eases frequency and intensity of hot flashes and supports cooler, more comfortable sleep.
How it Works: Improves thermoregulatory control and calms stress-related vasomotor fluctuations for nighttime comfort.
• Emotional Steadiness & Stress Resilience
How it Helps: Promotes a calm mood, reduces irritability, and provides steadier daytime energy.
How it Works: Helps regulate cortisol rhythms and stabilise stress-response signalling for emotional equilibrium.
• Menopausal Transition Support
How it Helps: Assists with mood swings, sleep disruption, and general menopausal discomfort.
How it Works: Encourages balanced hypothalamic–pituitary signalling and autonomic steadiness during hormonal shifts.
• Cognitive & Physical Vitality
How it Helps: Improves clarity, motivation, and energy, reducing fatigue associated with hormonal changes.
How it Works: Supports mitochondrial efficiency and balanced neurotransmitter activity to sustain stamina and focus.
• Sleep Quality & Restorative Recovery
How it Helps: Promotes restful sleep and more effortless relaxation during hormonal transitions.
How it Works: Calms neural overactivity and moderates nocturnal stress signals that disturb rest.
Non-Oestrogenic Assurance: This formula is designed to stabilise hormonal balance without adding phyto-oestrogens or mimicking oestrogen activity, making it suitable for oestrogen-sensitive women.
Key Ingredients – Evidence-Based Actions
• Ashwagandha (Withania somnifera)
How it Helps: Reduces climacteric symptoms (including stress, sleep issues, and vasomotor discomfort) and supports emotional balance.
Why it Works: Normalises HPA-axis/cortisol and supports GABAergic tone; RCTs show improvements in perimenopausal symptom scores.
Research:
– RCT: ashwagandha improved perimenopausal (“climacteric”) symptoms: https://pubmed.ncbi.nlm.nih.gov/34553463/
– Narrative review (Cambridge Media Journals) — working article page: https://journals.cambridgemedia.com.au/ajhnm/volume-37-issue-3/withania-somnifera-ashwagandha-safe-and-effective-treatment-reducing-perimenopausal-symptoms
• Maca (Lepidium meyenii)
How it Helps: Supports mood, energy, and menopausal comfort (including hot flashes/sexual function) as a supportive adaptogenic food.
Why it Works: Plant sterols and macamides may influence stress and central neurotransmission without acting as classic phyto-oestrogens; human evidence is mixed/modest.
Research:
– Systematic review of maca for menopausal symptoms (mixed but suggestive): https://pubmed.ncbi.nlm.nih.gov/21840656/
• Sage (Salvia officinalis)
How it Helps: Supports reduction in hot-flash frequency/intensity and improves thermoregulatory comfort.
Why it Works: Modulates central neurotransmitters involved in sweat/temperature control; clinical studies show improvements in hot flashes.
Research:
– Review summarising hot-flash improvements across multiple studies: https://pmc.ncbi.nlm.nih.gov/articles/PMC10363264/
– RCT with fresh-leaf ethanolic extract (Menosan®): https://www.sciencedirect.com/science/article/pii/S2405844021000153
• Dong Quai (Angelica sinensis)
How it Helps: Traditional pelvic-circulatory and comfort support during hormonal transitions.
Why it Works: Phytochemicals (e.g., ferulic acid) support microcirculation and smooth-muscle comfort; evidence for hot flashes alone is limited.
Research:
– Pilot trial: no significant benefit for hot flashes vs placebo: https://pmc.ncbi.nlm.nih.gov/articles/PMC2811999/
– Clinical overview & safety considerations (MSKCC): https://www.mskcc.org/cancer-care/integrative-medicine/herbs/dong-quai
• Tribulus (Tribulus terrestris)
How it Helps: May support libido and sexual function, aiding quality of life during menopausal transition.
Why it Works: Saponins may influence androgenic signalling and central arousal pathways; small RCTs in women show benefit on desire/function.
Research:
– RCT in women with hypoactive sexual desire disorder: https://pubmed.ncbi.nlm.nih.gov/24773615/
– Open-access RCT summary: https://pmc.ncbi.nlm.nih.gov/articles/PMC4045980/
• Chasteberry (Vitex agnus-castus)
How it Helps: Eases menopausal vasomotor symptoms (hot flashes/night sweats), supports emotional balance (anxiety/low mood), and promotes sleep quality during the transition.
Why it Works: Central dopaminergic modulation helps steady hypothalamic–pituitary signalling implicated in vasomotor instability and mood; emerging clinical data show reductions in vasomotor and anxiety scores in postmenopausal women.
Research:
– Randomised, placebo-controlled trial: vitex reduced total menopausal disorder and vasomotor dysfunction scores: https://pmc.ncbi.nlm.nih.gov/articles/PMC6887765/
– Clinical trial report: vitex reduced depression in postmenopausal women vs placebo: https://brieflands.com/articles/semj-103381
• Rhodiola (Rhodiola rosea)
How it Helps: Enhances stress resilience, mental energy, and perceived fatigue—useful for mood/energy dips around menopause.
Why it Works: Modulates stress-neurotransmission (e.g., HPA/monoamines); RCTs show improvements in stress-related fatigue and performance.
Research:
– Phase III RCT: stress-related fatigue improvements with SHR-5 extract: https://pubmed.ncbi.nlm.nih.gov/19016404/
• Passionflower (Passiflora incarnata)
How it Helps: Calms anxious tension and aids sleep onset, supporting emotional balance.
Why it Works: Flavonoids may enhance GABAergic signalling; head-to-head RCT suggests anxiolytic effects comparable to oxazepam with fewer performance side-effects.
Research:
– Double-blind RCT vs oxazepam in generalised anxiety: https://pubmed.ncbi.nlm.nih.gov/11679026/
Dosage Guidelines
• Prevention (daily balance): 1 capsule with breakfast.
• Maintenance (ongoing support): 1 capsule twice daily (morning & late afternoon).
• Therapeutic (active symptoms): 2 capsules morning + 1 capsule evening for 4–8 weeks, then reduce to Maintenance; seek clinician guidance for persistent/severe symptoms.
Tips: For hot-flash relief, ensure regular daytime hydration, reduce late-evening alcohol/caffeine, and pair with paced breathing or cooling strategies at night.
Warnings & Interactions
• Pregnancy & breastfeeding: Do not use (Vitex/dong quai/rhodiola/passionflower); they lack sufficient safety, and Vitex may affect lactation.
• Oestrogen-sensitive conditions (e.g., ER+ cancers, endometriosis, fibroids): This formula is designed to be low-oestrogenic; however, dong quai may have weak/variable oestrogen-like effects, avoid or use only under clinician supervision.
• Hormonal medicines: Use caution with dopamine agonists/antagonists (Vitex), HRT, or oral contraceptives; consult your clinician.
• Bleeding risk: Dong quai may increase bleeding tendency; caution with anticoagulants/antiplatelets or before surgery.
• CNS-active meds: Passionflower may enhance sedatives; rhodiola may be stimulating in some, avoid late-evening dosing.
• Thyroid/autoimmune: Ashwagandha may influence thyroid indices and rare immune reactions—monitor if on thyroid meds or with autoimmune disease.
• Allergy: Avoid if allergic to any listed herbs.
• Discontinue if adverse reactions occur. Keep out of reach of children.
⚠️ Disclaimer
Natural herbal supplement for general well-being.
Not intended to diagnose, treat, cure, or prevent any disease.
Statements reflect traditional use and general wellness support and have not been evaluated by SAHPRA.
Consult a healthcare professional before use—especially if pregnant, breastfeeding, on hormone-related therapies, anticoagulants, sedatives, thyroid medication, or managing oestrogen-sensitive conditions.
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