Ingredients: Liquorice Root, Cordyceps, Reishi, Lion’s Mane, Tulsi, Neem, Frankincense, Myrrh, Stinging Nettle, N-Acetylcysteine (NAC), Quercetin, Bromelain, Coenzyme Q10
Who It’s For
Adults seeking a natural, multi-pathway method to support cellular defence and immune resilience—enhancing the body’s ability to neutralise oxidative stress, maintain balanced inflammatory responses, and identify and eliminate unhealthy cells. Best used alongside a nutrient-rich diet, regular activity, restorative sleep, and professional guidance where necessary.
Health Benefits Summary
Cell Sync is designed to train, balance, and sustain immune function while protecting healthy cells. By priming innate surveillance and controlling cytokine signalling, it supports the effective identification of abnormal cells without overreacting. At the same time, strong cellular antioxidant defences (including glutathione renewal and lipid-phase protection) shield DNA, proteins, and membranes from free-radical damage, maintaining cell integrity and signalling. Targeted modulation of 5-LOX/COX pathways helps stabilise inflammatory responses for tissue comfort and recovery, while mucolytic and barrier-supporting actions strengthen clear, resilient airways—the body’s frontline defence. Lastly, support for mitochondrial electron transport and microcirculation helps preserve steady cellular energy and nutrient delivery during daily stress, promoting overall immune resilience and long-term cellular health.
Detailed Health Benefits
• Cellular Antioxidant Defence
How it Helps: Shields DNA, proteins, and cell membranes from oxidative stress, preserving cellular health and longevity.
How it Works: NAC rebuilds glutathione; quercetin and CoQ10 neutralise free radicals and stabilise mitochondrial energy pathways to protect cell structures.
• Immune Vigilance & Balance
How it Helps: Enhances immune intelligence—supporting efficient detection of unhealthy cells while keeping responses measured.
How it Works: β-glucans engage pattern-recognition receptors (e.g., Dectin-1), training innate cells (macrophages/NK) and moderating downstream cytokines.
• Healthy Inflammatory Response
How it Helps: Eases discomfort and supports tissue recovery when inflammation is overactive.
How it Works: Targeted 5-LOX/COX modulation steadies’ leukotriene and prostaglandin signalling for balanced inflammatory cascades.
• Mucosal & Respiratory Support
How it Helps: Promotes clear, comfortable airways and resilient mucosal barriers—key front-line immune defences.
How it Works: NAC reduces mucus viscosity and boosts antioxidant defences; soothing demulcents support epithelial integrity and barrier function.
• Circulation & Nutrient Delivery
How it Helps: Supports microcirculation to deliver oxygen and nutrients necessary for cellular repair and performance.
How it Works: Enzymatic and vaso-trophic actives assist tissue permeability and tone, aiding perfusion and recovery at the cellular level.
Key Ingredients — Evidence-Based Actions
• Liquorice Root (Glycyrrhiza glabra)
How it Helps: Calms overactive inflammation, supports antiviral defences, and protects irritated mucosal tissue.
Why it Works: Glycyrrhizin and flavonoids modulate NF-κB/COX-2/5-LOX signalling, enhance interferon responses, stabilise epithelial mucus, and influence 11β-HSD2 for stress-immune balance.
Research:
– Antiviral actions of glycyrrhizic acid: https://pmc.ncbi.nlm.nih.gov/articles/PMC10223068/
– Review: anti-inflammatory, antiviral, immunomodulator: https://pubmed.ncbi.nlm.nih.gov/35403088/
• Cordyceps (C. militaris / C. sinensis)
How it Helps: Primes innate immunity and sustains cellular energy under stress and exertion.
Why it Works: β-glucans and cordycepin engage PRRs (e.g., Dectin-1), support NK/macrophage function, and activate AMPK/adenosine pathways for mitochondrial output and cytokine balance.
Research:
– 2024 RCT (fermented C. militaris beverage): https://pubmed.ncbi.nlm.nih.gov/38580687/
– Immunomodulatory/anti-infective properties: https://pubmed.ncbi.nlm.nih.gov/39590481
• Reishi (Ganoderma lucidum)
How it Helps: Enhances immune surveillance while promoting a measured inflammatory tone.
Why it Works: β-1,3/1,6-glucans stimulate NK activity and complement; triterpenes (ganoderic acids) down-tune NF-κB/COX-2, guiding Th1/Th2/Treg balance.
Research:
– 2023 RCT: β-glucan immune modulation: https://pubmed.ncbi.nlm.nih.gov/36766186/
– Systematic review: host immune indices: https://pubmed.ncbi.nlm.nih.gov/27045603/
• Lion’s Mane (Hericium erinaceus)
How it Helps: Supports immune balance and neuronal resilience in the face of oxidative stress.
Why it Works: Polysaccharides modulate macrophage/T-cell signalling; hericenones/erinacines upregulate endogenous defences and limit lipid peroxidation.
Research:
– Immunomodulatory polysaccharides (preclinical): https://pubmed.ncbi.nlm.nih.gov/28266682/
– 2025 narrative review: antioxidant/anti-inflammatory potential: https://pmc.ncbi.nlm.nih.gov/articles/PMC12030463/
• Tulsi / Holy Basil (Ocimum tenuiflorum)
How it Helps: Eases stress-linked immune dysregulation and soothes airways/mucosa.
Why it Works: Eugenol, rosmarinic acid and terpenes temper NF-κB/COX-2, stabilise mast-cell mediator release, and normalise HPA-axis tone.
Research:
– DB-crossover RCT: immunomodulatory effects: https://pubmed.ncbi.nlm.nih.gov/21619917/
– Human overview & safety: https://pmc.ncbi.nlm.nih.gov/articles/PMC5376420/
• Neem (Azadirachta indica)
How it Helps: Supports microbial balance and healthy immune activation without excessive reactivity.
Why it Works: Limonoids (e.g., azadirachtin) and polysaccharides influence antibody responses and macrophage activity, potentially interfering with pathogen adhesion/quorum sensing.
Research:
– Review: therapeutic roles & immunomodulation: https://pmc.ncbi.nlm.nih.gov/articles/PMC4791507/
– Human data: neem oil as nonspecific immunostimulant: https://pubmed.ncbi.nlm.nih.gov/1452404/
• Frankincense (Boswellia serrata)
How it Helps: Reduces discomfort caused by overactive inflammation and supports tissue recovery.
Why it Works: Boswellic acids (AKBA) selectively inhibit 5-LOX and leukotriene synthesis, moderating neutrophil traffic and mediator cascades.
Research:
– Clinical study (ulcerative colitis): https://pubmed.ncbi.nlm.nih.gov/9049593/
– Systematic review: clinical effectiveness & safety: https://www.bmj.com/content/337/bmj.a2813
• Myrrh (Commiphora myrrha)
How it Helps: Tones and protects mucosal tissues; complements frankincense for inflammation balance.
Why it Works: Resin acids and furanosesquiterpenes modulate COX/LOX, show antimicrobial/biofilm-disrupting actions, and support local perfusion/repair.
Research:
– RCT (myrrh-chamomile-charcoal) vs mesalazine: https://pubmed.ncbi.nlm.nih.gov/23826890/
– Trial/remission maintenance in UC: https://pmc.ncbi.nlm.nih.gov/articles/PMC3373729/
• Stinging Nettle (Urtica dioica)
How it Helps: Promotes joint/tissue comfort, as well as overall antioxidant status, during immune challenges.
Why it Works: Polyphenols and lectins modulate NF-κB, COX-1/2, and 5-LOX signalling and scavenge ROS, thereby buffering cytokine surges.
Research:
– Review: anti-inflammatory mechanisms: https://pmc.ncbi.nlm.nih.gov/articles/PMC9253158/
– Overview: composition & bioactivities: https://pmc.ncbi.nlm.nih.gov/articles/PMC9413031/
• N-Acetylcysteine (NAC)
How it Helps: Rebuilds intracellular glutathione and supports clear, comfortable airways.
Why it Works: Provides cysteine for GSH synthesis (redox/phase-II detox) and breaks disulfide bonds in mucus; directly scavenges free radicals.
Research:
– DB-RCT: fewer influenza-like episodes: https://pubmed.ncbi.nlm.nih.gov/9230243/
– Review: oxidative-stress rationale: https://pmc.ncbi.nlm.nih.gov/articles/PMC7436914/
• Quercetin
How it Helps: Maintains immune resilience and eases exercise- or stress-related dips; supports balanced histamine responses.
Why it Works: Inhibits lipid peroxidation; modulates PI3K/Akt and NF-κB; stabilises mast cells to reduce histamine/cytokines.
Research:
– RCT: reduced URTI post-intense exercise: https://pubmed.ncbi.nlm.nih.gov/17805089/
– Review: immune mechanisms & prevention roles: https://pmc.ncbi.nlm.nih.gov/articles/PMC7392107/
• Bromelain
How it Helps: Assists with reducing swelling, improving tissue permeability, and promoting post-stress recovery.
Why it Works: Proteolytic enzymes reduce bradykinin/fibrin accumulation, influence prostaglandins/adhesion molecules, and may enhance absorption of co-nutrients (e.g., quercetin).
Research:
– Systematic review of RCTs (inflammatory markers): https://pubmed.ncbi.nlm.nih.gov/37202035/
– Clinical trial set summary: https://www.sciencedirect.com/science/article/abs/pii/S2405457723000591
• Coenzyme Q10
How it Helps: Supports steady cellular energy and protects lipid membranes from oxidative damage.
Why it Works: ETC cofactor (Complexes I–III) and lipid-phase antioxidant; helps regenerate vitamin E and activates Nrf2-linked defences.
Research:
– Meta-analysis: oxidative-stress biomarkers: https://pmc.ncbi.nlm.nih.gov/articles/PMC9311997/
– 2024 meta-analysis: muscle-damage/oxidative stress: https://pubmed.ncbi.nlm.nih.gov/38479900/
Dosage Guidelines
• Prevention: 1 capsule daily
• Maintenance: 1 capsule twice daily
• Therapeutic: 3 capsules daily
Warnings & Interactions
• Not for pregnancy or breastfeeding.
• Liquorice: May raise blood pressure and lower potassium; avoid with diuretics, corticosteroids, or heart/kidney disease.
• Mushrooms: Use caution with anticoagulants or immunosuppressants.
• Neem: Avoid in pregnancy or conception attempts; monitor blood sugar if diabetic.
• Frankincense/Myrrh: Theoretical bleeding risk—use caution with blood thinners.
• NAC: May enhance nitroglycerin effects; occasional GI upset possible.
• Quercetin/Bromelain: May alter drug absorption and clotting; caution with anticoagulants.
• CoQ10: May reduce warfarin effect—monitor INR with clinician oversight.
• Discontinue if adverse reactions occur. Keep out of reach of children.
⚠️ Disclaimer
Natural herbal supplement for general well-being.
Not intended to diagnose, treat, cure, or prevent any disease.
Statements reflect traditional use and general wellness support and have not been evaluated by SAHPRA.
Consult a healthcare professional before use—especially if pregnant, breastfeeding, on medication (including anticoagulant, antiplatelet, or immunosuppressive therapies), or managing a medical condition.
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