Ingredients: Hawthorn berries, Cayenne pepper, Guggulsterone (from guggul), Berberine, Coenzyme Q10, Green tea extract, Turmeric, Black pepper (piperine), Fenugreek
Who is it for?
Adults seeking natural support for heart health to maintain healthy cholesterol levels, support circulation, and protect the heart, ideal for those focused on lipid balance, oxidative stress reduction, and daily heart vitality, alongside a balanced diet, regular exercise, and medical advice when necessary.
Health Benefits Summary
Cardichol combines traditional cardiovascular herbs with modern nutraceuticals to support lipid metabolism, promote healthy blood flow, and protect the cardiovascular system from oxidative stress. Hawthorn and cayenne enhance circulatory tone and performance; berberine, green tea, turmeric, and fenugreek aid in maintaining healthy cholesterol and triglyceride levels; CoQ10 supports cellular energy and endothelial function; piperine improves the bioavailability of key active ingredients. The result is a practical, multi-pathway formula for cholesterol regulation and overall heart vitality.
Health Benefits Detailed
Healthy cholesterol profile
How it Helps: Supports normal LDL, HDL and triglyceride levels as part of a heart-healthy lifestyle.
Why it works: Berberine, green tea catechins, turmeric, and fenugreek help regulate lipid synthesis, uptake, and oxidation; piperine aids the absorption of co-actives.
Circulation & endothelial support
How it Helps: Encourages comfortable blood flow and exercise readiness.
Why it works: Hawthorn supports cardiac performance and vascular tone; capsaicin in cayenne influences nitric-oxide–related vasodilatory pathways; CoQ10 supports endothelial function.
Oxidative-stress defence
How it Helps: Protects lipids and vessel linings from free-radical damage.
Why it works: Polyphenols (found in green tea, turmeric, and fenugreek) and CoQ10 provide antioxidant activity that complements lifestyle measures.
Heart energy & stamina
How it Helps: Supports cellular energy in the heart and skeletal muscle for day-to-day vitality.
Why it works: CoQ10 is integral to mitochondrial electron transport, backing ATP generation in high-demand tissues.
Metabolic balance synergy
How it Helps: Complements diet and activity to maintain cardio-metabolic balance.
Why it works: Berberine and green tea support glucose–lipid interplay; turmeric and fenugreek add inflammation-modulating support.
Key Ingredients Benefits
• Hawthorn berries (Crataegus spp.)
How it Helps: Traditional heart tonic that supports cardiac performance and comfortable circulation.
Why it works: Oligomeric procyanidins and flavonoids modulate vascular tone and myocardial performance.
Research:
- Meta-analysis of clinical trials in heart failure (Crataegus extracts). https://pubmed.ncbi.nlm.nih.gov/12798455/
- Benefit–risk assessment of standardised Crataegus extract (WS 1442). https://pmc.ncbi.nlm.nih.gov/articles/PMC5772138/ (PubMed)
• Cayenne pepper (Capsicum annuum; capsaicinoids)
How it Helps: Gentle circulatory support and thermogenic back-up for an active lifestyle.
Why it works: Capsaicin engages TRPV1 pathways linked to nitric oxide signalling and vascular responsiveness.
Research:
- Review: capsicum/capsaicin and cardiometabolic risk factors. https://pmc.ncbi.nlm.nih.gov/articles/PMC4893589/
- Review/overview of capsaicin’s vascular mechanisms (NO/eNOS). https://pubmed.ncbi.nlm.nih.gov/36007275/ (PMC)
• Guggulsterone (from Commiphora mukul)
How it Helps: Traditional lipid support; modern evidence is mixed and may be neutral or unfavourable.
Why it works: Historically proposed to influence bile acid and cholesterol metabolism; high-quality trials show variable effects.
Research:
- Randomised, double-blind, placebo-controlled trial in hypercholesterolemia: LDL increased vs placebo. https://pubmed.ncbi.nlm.nih.gov/12915429/
- Review noting LDL increases in the above RCT. https://pubmed.ncbi.nlm.nih.gov/16338199/ (PubMed)
• Berberine (isoquinoline alkaloid, e.g., from Berberis spp.)
How it Helps: Supports healthy levels of LDL and triglycerides, promoting broader cardiometabolic balance.
Why it works: Activates AMPK and down-regulates PCSK9, aiding lipid handling and clearance.
Research:
- 2024 meta-analysis: lipid-lowering effects of berberine (PCSK9-related). https://pubmed.ncbi.nlm.nih.gov/37183391/
- 2025 meta-analysis on metabolic-syndrome components (TG, fasting glucose, waist). https://pubmed.ncbi.nlm.nih.gov/40740996/ (PubMed)
• Coenzyme Q10 (ubiquinone)
How it Helps: Supports endothelial function and healthy blood pressure profiles; promotes cellular energy in the myocardium.
Why it works: Central to mitochondrial electron transport and may improve flow-mediated dilation (FMD).
Research:
- 2024 meta-analysis: CoQ10 improved FMD (endothelial function). https://pubmed.ncbi.nlm.nih.gov/38630421/
- 2025 meta-analysis: reductions in systolic blood pressure with supplementation. https://pubmed.ncbi.nlm.nih.gov/40495903/ (PubMed)
• Green tea extract (Camellia sinensis; catechins/EGCG)
How it Helps: Modestly lowers LDL and supports vascular antioxidant defence.
Why it works: Catechins reduce intestinal lipid absorption and hepatic lipid synthesis; antioxidant effects protect LDL from oxidation.
Research:
- Meta-analysis of randomised trials: lowered total and LDL cholesterol. https://pmc.ncbi.nlm.nih.gov/articles/PMC7240975/
- 2023 meta-analysis: significant LDL reduction across clinical trials. https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.1084455/full (PMC)
• Turmeric (Curcuma longa; curcuminoids)
How it Helps: Adjunct support for healthy lipids and inflammation balance.
Why it works: Curcuminoids modulate NF-κB and lipid-regulatory enzymes, with small but meaningful lipid effects in pooled trials.
Research:
- 2023 meta-analysis of RCTs: improvements in TC, TG, LDL and HDL. https://pubmed.ncbi.nlm.nih.gov/37230418/
- 2025 umbrella review/meta-analysis on lipids. https://pmc.ncbi.nlm.nih.gov/articles/PMC12241857/ (PubMed)
• Black pepper (Piper nigrum; piperine)
How it Helps: Bioavailability enhancer that raises systemic levels of co-actives (e.g., curcumin), supporting overall efficacy.
Why it works: Piperine inhibits glucuronidation and intestinal efflux transporters.
Research:
- Human study: ~2000% increase in curcumin bioavailability with 20 mg piperine. https://pubmed.ncbi.nlm.nih.gov/9619120/
- Overview of piperine as a natural bioenhancer. https://pmc.ncbi.nlm.nih.gov/articles/PMC3634921/ (PubMed)
• Fenugreek (Trigonella foenum-graecum)
How it Helps: Supports a healthier balance of LDL/TG and HDL while also assisting in glycemic control.
Why it works: Soluble fibre (galactomannans) and 4-hydroxy-isoleucine influence bile acid recycling, carbohydrate handling, and lipid metabolism.
Research:
- 2020 meta-analysis: fenugreek improved LDL, TG, TC and HDL. https://pubmed.ncbi.nlm.nih.gov/32385866/
- 2024 meta-analysis in type 2 diabetes: reductions in total and LDL cholesterol. https://pmc.ncbi.nlm.nih.gov/articles/PMC11403534/ (PubMed)
Dosage
• Prevention: 1 capsule daily
• Maintenance: 1 capsule twice daily
• Therapeutic: 3 capsules daily
Warnings & Interactions
• Not for pregnancy or breastfeeding.
• Heart medicines: Hawthorn may potentiate effects of blood-pressure or cardiac medicines, use with professional guidance.
• Liver/thyroid: Guggul/guggulsterone may affect liver enzymes and thyroid hormones; evidence for cholesterol benefit is mixed.
• Glucose-lowering meds: Berberine and fenugreek may enhance glucose-lowering. Monitor with a clinician.
• Anticoagulants/antiplatelets: Turmeric, green tea extract and bromelain-like enzymes/spices may increase bleeding risk, use with caution.
• CoQ10 & warfarin: CoQ10 may reduce warfarin’s effect, monitor INR.
• Green tea extract: Contains caffeine; rare reports of liver enzyme elevations at high doses, avoid if you have active liver disease unless supervised.
• Black pepper (piperine): May increase drug bioavailability, separate medicines by 2+ hours and seek advice if on chronic therapy.
• Stop use if any adverse reaction occurs.
⚠️ Disclaimer
Natural herbal supplement for general well-being. Not intended to diagnose, treat, cure, or prevent any disease. Statements reflect traditional use and general wellness support and have not been evaluated by SAHPRA. Consult a healthcare professional before use, especially if pregnant, nursing, on medication (including heart, blood-pressure, anticoagulant or thyroid therapies), or managing a medical condition. Keep out of reach of children.